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Systems Biology

01 September 2018

This course is an introduction to the theoretical tools that are used to understand the emerging behavior of complex biological networks. Systems Biology is a systemic approach to understand the biological phenomena that occurs inside a cell at the molecular level.

Slides used in classes

Most classes are done on a whiteboard, so you need to keep your own paper copy. Some of these classes are later transcribed into webpage and published here. When the class used slides, they are published here.

Example Jupyter code

Online material


The forum of the course is at You can also participate writing an email to . Feel free to use it to ask any question or give any answer.

Transcriptional Regulation

  • Which genes code for transcription factors?
  • Which are their binding sites?
  • How do they change gene expression?
    • enhancer
    • repressor

Binding Sites

  • Few experimental results. Expensive
  • How can we generalize them?
    • Probability theory
    • other approaches