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Systems Biology

From genotype to phenotype.

23 September 2021

Systems Biology is a systemic approach to understand the biological phenomena that occurs inside a cell at the molecular level. This course is an introduction to the theoretical tools that are used to understand the emerging behavior of complex biological networks.

The schedule is Tuesdays at 11:00 and Fridays at 15:00 via Zoom.

We have finished the first part of the course, about gene expression analysis using linear models. Now we will study biological networks. A good overview of the subject is available on the following paper. Please read it before the next class.

Albert, Réka. “Network Inference, Analysis, and Modeling in Systems Biology.” The Plant Cell 19, no. 11 (2007): 3327–38.

Slides used in classes

[Video],[Slides]. + Class 17: Normalization in Arrays. (Dec 21, 2021). A practical session. [Video],[Slides]. + Class 19: Normalization in RNAseq. (Dec 28, 2021). Last class. [Slides].

Online material


Suggested, but not Essential



The forum of the course is at You can also participate writing an email to . Feel free to use it to ask any question or give any answer>.

Topics to be discussed